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Whole-Transcriptome Analysis Highlights Adenylyl Cyclase Toxins-Derived Modulation of NF-κB and ERK1/2 Pathways in Macrophages
Edema toxin (ET), one of the main toxic factors of Bacillus anthracis (B. anthracis), is a kind of potent adenylate cyclase (AC). B. anthracis has adapted to resist macrophage microbicidal mechanisms in part by secreting ET. To date, there is limited information on the pathogenic mechanisms used by...
Autores principales: | Zhao, Taoran, Li, Ruihua, Qian, Mengyin, Wang, Meirong, Zhang, Xiaozheng, Wang, Yuhan, Zhao, Xinghui, Xie, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967024/ https://www.ncbi.nlm.nih.gov/pubmed/36828453 http://dx.doi.org/10.3390/toxins15020139 |
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