Development and Comparative In Vitro and In Vivo Study of BNN27 Mucoadhesive Liposomes and Nanoemulsions for Nose-to-Brain Delivery

Intranasal administration offers an alternative and promising approach for direct nose-to-brain delivery. Herein, we developed two chitosan (CHT)-coated (and uncoated) nanoformulations of BNN27 (a synthetic C-17-spiro-dehydroepiandrosterone analogue), liposomes (LIPs), and nanoemulsions (NEs), and c...

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Detalles Bibliográficos
Autores principales: Kannavou, Maria, Karali, Kanelina, Katsila, Theodora, Siapi, Eleni, Marazioti, Antonia, Klepetsanis, Pavlos, Calogeropoulou, Theodora, Charalampopoulos, Ioannis, Antimisiaris, Sophia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967044/
https://www.ncbi.nlm.nih.gov/pubmed/36839740
http://dx.doi.org/10.3390/pharmaceutics15020419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967044/
https://www.ncbi.nlm.nih.gov/pubmed/36839740
http://dx.doi.org/10.3390/pharmaceutics15020419

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