Developmentally Programmed Switches in DNA Replication: Gene Amplification and Genome-Wide Endoreplication in Tetrahymena

Locus-specific gene amplification and genome-wide endoreplication generate the elevated copy number of ribosomal DNA (rDNA, 9000 C) and non-rDNA (90 C) chromosomes in the developing macronucleus of Tetrahymena thermophila. Subsequently, all macronuclear chromosomes replicate once per cell cycle duri...

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Detalles Bibliográficos
Autores principales: Meng, Xiangzhou, Dang, Hung Quang, Kapler, Geoffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967165/
https://www.ncbi.nlm.nih.gov/pubmed/36838456
http://dx.doi.org/10.3390/microorganisms11020491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967165/
https://www.ncbi.nlm.nih.gov/pubmed/36838456
http://dx.doi.org/10.3390/microorganisms11020491

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