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Developmentally Programmed Switches in DNA Replication: Gene Amplification and Genome-Wide Endoreplication in Tetrahymena

Locus-specific gene amplification and genome-wide endoreplication generate the elevated copy number of ribosomal DNA (rDNA, 9000 C) and non-rDNA (90 C) chromosomes in the developing macronucleus of Tetrahymena thermophila. Subsequently, all macronuclear chromosomes replicate once per cell cycle duri...

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Detalles Bibliográficos
Autores principales:	Meng, Xiangzhou, Dang, Hung Quang, Kapler, Geoffrey M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967165/ https://www.ncbi.nlm.nih.gov/pubmed/36838456 http://dx.doi.org/10.3390/microorganisms11020491

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