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Unveiling the Machinery behind Chromosome Folding by Polymer Physics Modeling

Understanding the mechanisms underlying the complex 3D architecture of mammalian genomes poses, at a more fundamental level, the problem of how two or multiple genomic sites can establish physical contacts in the nucleus of the cells. Beyond stochastic and fleeting encounters related to the polymeri...

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Detalles Bibliográficos
Autores principales: Conte, Mattia, Esposito, Andrea, Vercellone, Francesca, Abraham, Alex, Bianco, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967178/
https://www.ncbi.nlm.nih.gov/pubmed/36835064
http://dx.doi.org/10.3390/ijms24043660