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Unveiling the Machinery behind Chromosome Folding by Polymer Physics Modeling
Understanding the mechanisms underlying the complex 3D architecture of mammalian genomes poses, at a more fundamental level, the problem of how two or multiple genomic sites can establish physical contacts in the nucleus of the cells. Beyond stochastic and fleeting encounters related to the polymeri...
Autores principales: | Conte, Mattia, Esposito, Andrea, Vercellone, Francesca, Abraham, Alex, Bianco, Simona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967178/ https://www.ncbi.nlm.nih.gov/pubmed/36835064 http://dx.doi.org/10.3390/ijms24043660 |
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