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Screening the Pathogen Box to Discover and Characterize New Cruzain and TbrCatL Inhibitors
Chagas disease and Human African Trypanosomiasis, caused by Trypanosoma cruzi and T. brucei, respectively, pose relevant health challenges throughout the world, placing 65 to 70 million people at risk each. Given the limited efficacy and severe side effects associated with current chemotherapy, new...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967275/ https://www.ncbi.nlm.nih.gov/pubmed/36839523 http://dx.doi.org/10.3390/pathogens12020251 |