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Screening the Pathogen Box to Discover and Characterize New Cruzain and TbrCatL Inhibitors

Chagas disease and Human African Trypanosomiasis, caused by Trypanosoma cruzi and T. brucei, respectively, pose relevant health challenges throughout the world, placing 65 to 70 million people at risk each. Given the limited efficacy and severe side effects associated with current chemotherapy, new...

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Detalles Bibliográficos
Autores principales: do Valle Moreira, Thales, Martins, Luan Carvalho, Diniz, Lucas Abreu, Bernardes, Talita Cristina Diniz, de Oliveira, Renata Barbosa, Ferreira, Rafaela Salgado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967275/
https://www.ncbi.nlm.nih.gov/pubmed/36839523
http://dx.doi.org/10.3390/pathogens12020251