Molecular Dynamic Simulation Analysis of a Novel Missense Variant in CYB5R3 Gene in Patients with Methemoglobinemia

Background and Objective: Mutations in the CYB5R3 gene cause reduced NADH-dependent cytochrome b5 reductase enzyme function and consequently lead to recessive congenital methemoglobinemia (RCM). RCM exists as RCM type I (RCM1) and RCM type II (RCM2). RCM1 leads to higher methemoglobin levels causing...

Descripción completa

Detalles Bibliográficos
Autores principales: Ullah, Asmat, Shah, Abid Ali, Syed, Fibhaa, Mahmood, Arif, Ur Rehman, Hassan, Khurshid, Beenish, Samad, Abdus, Ahmad, Wasim, Basit, Sulman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967277/
https://www.ncbi.nlm.nih.gov/pubmed/36837579
http://dx.doi.org/10.3390/medicina59020379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967277/
https://www.ncbi.nlm.nih.gov/pubmed/36837579
http://dx.doi.org/10.3390/medicina59020379

Ejemplares similares