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Iodide Excess Inhibits Thyroid Hormone Synthesis Pathway Involving XBP1-Mediated Regulation

Iodine is an essential micronutrient for producing thyroid hormone (TH); however, iodide excess can lead to adverse thyroidal effects. Unfortunately, the lack of a proper in vitro model system hampered the studies of the effect of iodide excess on thyroid physiology and pathology. Here, we demonstra...

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Detalles Bibliográficos
Autores principales: Yu, Jing, Shen, Siyi, Yan, Ying, Liu, Lingxiao, Luo, Rongkui, Liu, Shengnan, Wu, Yuting, Li, Yuying, Jiang, Jingjing, Ying, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967305/
https://www.ncbi.nlm.nih.gov/pubmed/36839245
http://dx.doi.org/10.3390/nu15040887