7S,15R-Dihydroxy-16S,17S-epoxy-docosapentaenoic Acid Overcomes Chemoresistance of 5-Fluorouracil by Suppressing the Infiltration of Tumor-Associated Macrophages and Inhibiting the Activation of Cancer Stem Cells in a Colorectal Cancer Xenograft Model

Although the tumor bulk is initially reduced by 5-fluorouracil (5-FU), chemoresistance developed due to prolonged chemotherapy in colorectal cancer (CRC). The enrichment of cancer stem cells (CSCs) and the infiltration of tumor-associated macrophages (TAMs) contribute to chemoresistance and poor out...

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Detalles Bibliográficos
Autores principales: Su, Yan, Choi, Hack Sun, Choi, Jong Hyun, Kim, Hee-Sik, Jang, Yong-Suk, Seo, Jeong-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967312/
https://www.ncbi.nlm.nih.gov/pubmed/36827121
http://dx.doi.org/10.3390/md21020080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967312/
https://www.ncbi.nlm.nih.gov/pubmed/36827121
http://dx.doi.org/10.3390/md21020080

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