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Radiolysis-Associated Decrease in Radiochemical Purity of (177)Lu-Radiopharmaceuticals and Comparison of the Effectiveness of Selected Quenchers against This Process

The radiolytic degradation of vector molecules is a major factor affecting the shelf life of therapeutic radiopharmaceuticals. The development of time-stable dosage forms of radiopharmaceuticals is the key to their successful implementation in clinical practice. Using [(177)Lu]Lu-PSMA-617 molecule a...

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Detalles Bibliográficos
Autores principales: Larenkov, Anton, Mitrofanov, Iurii, Pavlenko, Ekaterina, Rakhimov, Marat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967390/
https://www.ncbi.nlm.nih.gov/pubmed/36838872
http://dx.doi.org/10.3390/molecules28041884