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Three-Dimensional Analysis of Sex- and Gonadal Status- Dependent Microglial Activation in a Mouse Model of Parkinson’s Disease

Parkinson’s disease (PD) is characterized by neurodegeneration and neuroinflammation. PD prevalence and incidence are higher in men than in women and modulation of gonadal hormones could have an impact on the disease course. This was investigated in male and female gonadectomized (GDX) and SHAM oper...

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Detalles Bibliográficos
Autores principales: Isenbrandt, Amandine, Coulombe, Katherine, Morissette, Marc, Bourque, Mélanie, Lamontagne-Proulx, Jérôme, Di Paolo, Thérèse, Soulet, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967417/
https://www.ncbi.nlm.nih.gov/pubmed/37259303
http://dx.doi.org/10.3390/ph16020152