Decreased Levels of Chaperones in Mucopolysaccharidoses and Their Elevation as a Putative Auxiliary Therapeutic Approach

Mucopolysaccharidoses (MPS) are rare genetic disorders belonging to the lysosomal storage diseases. They are caused by mutations in genes encoding lysosomal enzymes responsible for degrading glycosaminoglycans (GAGs). As a result, GAGs accumulate in lysosomes, leading to impairment of cells, organs...

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Detalles Bibliográficos
Autores principales: Żabińska, Magdalena, Gaffke, Lidia, Bielańska, Patrycja, Podlacha, Magdalena, Rintz, Estera, Cyske, Zuzanna, Węgrzyn, Grzegorz, Pierzynowska, Karolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967431/
https://www.ncbi.nlm.nih.gov/pubmed/36840025
http://dx.doi.org/10.3390/pharmaceutics15020704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967431/
https://www.ncbi.nlm.nih.gov/pubmed/36840025
http://dx.doi.org/10.3390/pharmaceutics15020704

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