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A Synthetic Biology Approach for Vaccine Candidate Design against Delta Strain of SARS-CoV-2 Revealed Disruption of Favored Codon Pair as a Better Strategy over Using Rare Codons

The SARS-CoV-2 delta variant (B.1.617.2) appeared for the first time in December 2020 and later spread worldwide. Currently available vaccines are not so efficacious in curbing the viral pathogenesis of the delta strain of COVID; therefore, the development of a safe and effective vaccine is required...

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Detalles Bibliográficos
Autores principales: Gurjar, Pankaj, Karuvantevida, Noushad, Rzhepakovsky, Igor Vladimirovich, Khan, Azmat Ali, Khandia, Rekha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967482/
https://www.ncbi.nlm.nih.gov/pubmed/36851364
http://dx.doi.org/10.3390/vaccines11020487