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On the Physical Stability of Leucine-Containing Spray-Dried Powders for Respiratory Drug Delivery

Carrier-free spray-dried dispersions for pulmonary delivery, for which the demand is growing, frequently require the incorporation of dispersibility-enhancing excipients into the formulations to improve the efficacy of the dosage form. One of the most promising of such excipients, L-leucine, is expe...

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Detalles Bibliográficos
Autores principales: Ordoubadi, Mani, Shepard, Kimberly B., Wang, Hui, Wang, Zheng, Pluntze, Amanda M., Churchman, Joseph P., Vehring, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967520/
https://www.ncbi.nlm.nih.gov/pubmed/36839756
http://dx.doi.org/10.3390/pharmaceutics15020435