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On the Physical Stability of Leucine-Containing Spray-Dried Powders for Respiratory Drug Delivery
Carrier-free spray-dried dispersions for pulmonary delivery, for which the demand is growing, frequently require the incorporation of dispersibility-enhancing excipients into the formulations to improve the efficacy of the dosage form. One of the most promising of such excipients, L-leucine, is expe...
Autores principales: | Ordoubadi, Mani, Shepard, Kimberly B., Wang, Hui, Wang, Zheng, Pluntze, Amanda M., Churchman, Joseph P., Vehring, Reinhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967520/ https://www.ncbi.nlm.nih.gov/pubmed/36839756 http://dx.doi.org/10.3390/pharmaceutics15020435 |
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