Extracellular Histone-Induced Protein Kinase C Alpha Activation and Troponin Phosphorylation Is a Potential Mechanism of Cardiac Contractility Depression in Sepsis

Reduction in cardiac contractility is common in severe sepsis. However, the pathological mechanism is still not fully understood. Recently it has been found that circulating histones released after extensive immune cell death play important roles in multiple organ injury and disfunction, particularl...

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Detalles Bibliográficos
Autores principales: Abrams, Simon T., Alhamdi, Yasir, Zi, Min, Guo, Fengmei, Du, Min, Wang, Guozheng, Cartwright, Elizabeth J., Toh, Cheng-Hock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967552/
https://www.ncbi.nlm.nih.gov/pubmed/36834636
http://dx.doi.org/10.3390/ijms24043225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967552/
https://www.ncbi.nlm.nih.gov/pubmed/36834636
http://dx.doi.org/10.3390/ijms24043225

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