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Influence of the Fatty Acid Metabolism on the Mode of Action of a Cisplatin(IV) Complex with Phenylbutyrate as Axial Ligands

For a variety of cancer types, platinum compounds are still among the best treatment options. However, their application is limited by side effects and drug resistance. Consequently, multi-targeted platinum(IV) prodrugs that target specific traits of the malignant tissue are interesting new candidat...

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Detalles Bibliográficos
Autores principales: Mendrina, Theresa, Poetsch, Isabella, Schueffl, Hemma, Baier, Dina, Pirker, Christine, Ries, Alexander, Keppler, Bernhard K., Kowol, Christian R., Gibson, Dan, Grusch, Michael, Berger, Walter, Heffeter, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967619/
https://www.ncbi.nlm.nih.gov/pubmed/36839999
http://dx.doi.org/10.3390/pharmaceutics15020677