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Disulfiram Enhances the Antineoplastic Activity and Sensitivity of Murine Hepatocellular Carcinoma to 5-FU via Redox Management

The efficacy of anticancer drug 5-FU is suppressed due to various factors, including severe side effects and decreased insensitivity during prolonged chemotherapy. Elevated endogenous copper (Cu) levels are one of the prominent hallmark features of cancer cells. In the present investigation, this fe...

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Detalles Bibliográficos
Autores principales: Hassan, Iftekhar, Ebaid, Hossam, Alhazza, Ibrahim M., Al-Tamimi, Jameel, Rady, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967644/
https://www.ncbi.nlm.nih.gov/pubmed/37259318
http://dx.doi.org/10.3390/ph16020169