Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies

Targeting cancer cells that are highly dependent on the nicotinamide adenine dinucleotide (NAD+) metabolite is a promising therapeutic strategy. Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme catalyzing NAD(+) production. Despite the high efficacy of several developed NAM...

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Detalles Bibliográficos
Autores principales: Biniecka, Paulina, Matsumoto, Saki, Belotti, Axel, Joussot, Jessie, Bai, Jian Fei, Majjigapu, Somi Reddy, Thoueille, Paul, Spaggiari, Dany, Desfontaine, Vincent, Piacente, Francesco, Bruzzone, Santina, Cea, Michele, Decosterd, Laurent A., Vogel, Pierre, Nencioni, Alessio, Duchosal, Michel A., Nahimana, Aimable
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967653/
https://www.ncbi.nlm.nih.gov/pubmed/36838885
http://dx.doi.org/10.3390/molecules28041897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967653/
https://www.ncbi.nlm.nih.gov/pubmed/36838885
http://dx.doi.org/10.3390/molecules28041897

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