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Crucial Role of Lysine-Specific Histone Demethylase 1 in RANKL-Mediated Osteoclast Differentiation

Epigenetic regulators are involved in osteoclast differentiation. This study proposes that the inhibitors of epigenetic regulators could be effective in the treatment of osteoporosis. This study identified GSK2879552, a lysine-specific histone demethylase 1 (LSD1) inhibitor, as a candidate for the t...

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Detalles Bibliográficos
Autores principales: Ding, Mina, Chen, Zhihao, Cho, Eunjin, Park, Sang-Wook, Lee, Tae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967819/
https://www.ncbi.nlm.nih.gov/pubmed/36835016
http://dx.doi.org/10.3390/ijms24043605