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HIV-1 Gag Binds the Multi-Aminoacyl-tRNA Synthetase Complex via the EPRS Subunit

Host factor tRNAs facilitate the replication of retroviruses such as human immunodeficiency virus type 1 (HIV-1). HIV-1 uses human tRNA(Lys3) as the primer for reverse transcription, and the assembly of HIV-1 structural protein Gag at the plasma membrane (PM) is regulated by matrix (MA) domain–tRNA...

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Detalles Bibliográficos
Autores principales: Jin, Danni, Zhu, Yiping, Schubert, Heidi L., Goff, Stephen P., Musier-Forsyth, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967848/
https://www.ncbi.nlm.nih.gov/pubmed/36851687
http://dx.doi.org/10.3390/v15020474