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Sirolimus-Embedded Silk Microneedle Wrap to Prevent Neointimal Hyperplasia in Vein Graft Model

We investigated the role of a sirolimus-embedded silk microneedle (MN) wrap as an external vascular device for drug delivery efficacy, inhibition of neointimal hyperplasia, and vascular remodeling. Using dogs, a vein graft model was developed to interpose the carotid or femoral artery with the jugul...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Hwan, Jang, Eui Hwa, Ryu, Ji-Yeon, Lee, Jiyong, Kim, Jae Ho, Ryu, Wonhyoung, Youn, Young-Nam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967879/
https://www.ncbi.nlm.nih.gov/pubmed/36834717
http://dx.doi.org/10.3390/ijms24043306