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Sirolimus-Embedded Silk Microneedle Wrap to Prevent Neointimal Hyperplasia in Vein Graft Model
We investigated the role of a sirolimus-embedded silk microneedle (MN) wrap as an external vascular device for drug delivery efficacy, inhibition of neointimal hyperplasia, and vascular remodeling. Using dogs, a vein graft model was developed to interpose the carotid or femoral artery with the jugul...
Autores principales: | Kim, Jung-Hwan, Jang, Eui Hwa, Ryu, Ji-Yeon, Lee, Jiyong, Kim, Jae Ho, Ryu, Wonhyoung, Youn, Young-Nam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967879/ https://www.ncbi.nlm.nih.gov/pubmed/36834717 http://dx.doi.org/10.3390/ijms24043306 |
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