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Impact of Prenatal Exposure to Maternal Diabetes and High-Fat Diet on Postnatal Myocardial Ketone Body Metabolism in Rats

Infants exposed to diabetic pregnancy are at higher risk of cardiomyopathy at birth and early onset cardiovascular disease (CVD) as adults. Using a rat model, we showed how fetal exposure to maternal diabetes causes cardiac disease through fuel-mediated mitochondrial dysfunction, and that a maternal...

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Detalles Bibliográficos
Autores principales: Ayyappan, Prathapan, Larsen, Tricia D., Gandy, Tyler C. T., Louwagie, Eli J., Baack, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967912/
https://www.ncbi.nlm.nih.gov/pubmed/36835096
http://dx.doi.org/10.3390/ijms24043684