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Measuring Creatinine Clearance Is the Most Accurate Way for Calculating the Proper Continuous Infusion Meropenem Dose for Empirical Treatment of Severe Gram-Negative Infections among Critically Ill Patients

Assessment of glomerular filtration rate (GFR) is necessary for dose adjustments of beta-lactam that are excreted by the kidneys, such as meropenem. The aim of this study was to compare the daily dose of 24 h-continuous infusion (CI) meropenem when GFR was calculated by means of measured creatinine...

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Detalles Bibliográficos
Autores principales: Troisi, Carla, Cojutti, Pier Giorgio, Rinaldi, Matteo, Laici, Cristiana, Siniscalchi, Antonio, Viale, Pierluigi, Pea, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967919/
https://www.ncbi.nlm.nih.gov/pubmed/36839872
http://dx.doi.org/10.3390/pharmaceutics15020551