A Novel Preclinical In Vitro 3D Model of Oral Carcinogenesis for Biomarker Discovery and Drug Testing

This study aimed to develop an in vitro three-dimensional (3D) cell culture model of oral carcinogenesis for the rapid, scalable testing of chemotherapeutic agents. Spheroids of normal (HOK) and dysplastic (DOK) human oral keratinocytes were cultured and treated with 4-nitroquinoline-1-oxide (4NQO)....

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Detalles Bibliográficos
Autores principales: Chitturi Suryaprakash, Ravi Teja, Shearston, Kate, Farah, Camile S., Fox, Simon A., Iqbal, Muhammad Munir, Kadolsky, Ulrich, Zhong, Xiao, Saxena, Alka, Kujan, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967961/
https://www.ncbi.nlm.nih.gov/pubmed/36835505
http://dx.doi.org/10.3390/ijms24044096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967961/
https://www.ncbi.nlm.nih.gov/pubmed/36835505
http://dx.doi.org/10.3390/ijms24044096

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