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Lipopolyplex-Mediated Co-Delivery of Doxorubicin and FAK siRNA to Enhance Therapeutic Efficiency of Treating Colorectal Cancer

Tumor metastasis is a major concern in cancer therapy. In this context, focal adhesion kinase (FAK) gene overexpression, which mediates cancer cell migration and invasion, has been reported in several human tumors and is considered a potential therapeutic target. However, gene-based treatment has ce...

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Detalles Bibliográficos
Autores principales: Debele, Tilahun Ayane, Chen, Chi-Kang, Yu, Lu-Yi, Lo, Chun-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968081/
https://www.ncbi.nlm.nih.gov/pubmed/36839918
http://dx.doi.org/10.3390/pharmaceutics15020596