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Human Hepatocyte Nuclear Factors (HNF1 and LXRb) Regulate CYP7A1 in HIV-Infected Black South African Women with Gallstone Disease: A Preliminary Study

Female sex, high estrogen levels, aging, obesity, and dyslipidemia are some of the risk factors associated with gallstone formation. HIV-infected patients on combination antiretroviral therapy (cART) are more prone to hypercholesterolemia. Bile acid synthesis is initiated by cholesterol 7-alpha hydr...

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Detalles Bibliográficos
Autores principales: Kinoo, Suman Mewa, Naidoo, Pragalathan, Singh, Bhugwan, Chuturgoon, Anil, Nagiah, Savania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968087/
https://www.ncbi.nlm.nih.gov/pubmed/36836631
http://dx.doi.org/10.3390/life13020273