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Design, Synthesis, and Biological Evaluation of a Small-Molecule PET Agent for Imaging PD-L1 Expression

Immunotherapy blocking programmed cell death protein 1/programmed death ligand 1 (PD-1/PD-L1) pathway has achieved great therapeutic effect in the clinic, but the overall response rate is not satisfactory. Early studies showed that response to treatment and overall survival could be positively relat...

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Detalles Bibliográficos
Autores principales: Xu, Liang, Zhang, Lixia, Liang, Beibei, Zhu, Shiyu, Lv, Gaochao, Qiu, Ling, Lin, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968138/
https://www.ncbi.nlm.nih.gov/pubmed/37259361
http://dx.doi.org/10.3390/ph16020213