Homologous Recombination Deficiency in Ovarian Cancer: from the Biological Rationale to Current Diagnostic Approaches

The inability to efficiently repair DNA double-strand breaks using the homologous recombination repair pathway is defined as homologous recombination deficiency (HRD). This molecular phenotype represents a positive predictive biomarker for the clinical use of poly (adenosine diphosphate [ADP]-ribose...

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Detalles Bibliográficos
Autores principales: Mangogna, Alessandro, Munari, Giada, Pepe, Francesco, Maffii, Edoardo, Giampaolino, Pierluigi, Ricci, Giuseppe, Fassan, Matteo, Malapelle, Umberto, Biffi, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968181/
https://www.ncbi.nlm.nih.gov/pubmed/36836518
http://dx.doi.org/10.3390/jpm13020284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968181/
https://www.ncbi.nlm.nih.gov/pubmed/36836518
http://dx.doi.org/10.3390/jpm13020284

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