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Homologous Recombination Deficiency in Ovarian Cancer: from the Biological Rationale to Current Diagnostic Approaches
The inability to efficiently repair DNA double-strand breaks using the homologous recombination repair pathway is defined as homologous recombination deficiency (HRD). This molecular phenotype represents a positive predictive biomarker for the clinical use of poly (adenosine diphosphate [ADP]-ribose...
Autores principales: | Mangogna, Alessandro, Munari, Giada, Pepe, Francesco, Maffii, Edoardo, Giampaolino, Pierluigi, Ricci, Giuseppe, Fassan, Matteo, Malapelle, Umberto, Biffi, Stefania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968181/ https://www.ncbi.nlm.nih.gov/pubmed/36836518 http://dx.doi.org/10.3390/jpm13020284 |
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