FUS Alters circRNA Metabolism in Human Motor Neurons Carrying the ALS-Linked P525L Mutation

Deregulation of RNA metabolism has emerged as one of the key events leading to the degeneration of motor neurons (MNs) in Amyotrophic Lateral Sclerosis (ALS) disease. Indeed, mutations on RNA-binding proteins (RBPs) or on proteins involved in aspects of RNA metabolism account for the majority of fam...

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Detalles Bibliográficos
Autores principales: Colantoni, Alessio, Capauto, Davide, Alfano, Vincenzo, D’Ambra, Eleonora, D’Uva, Sara, Tartaglia, Gian Gaetano, Morlando, Mariangela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968238/
https://www.ncbi.nlm.nih.gov/pubmed/36834591
http://dx.doi.org/10.3390/ijms24043181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968238/
https://www.ncbi.nlm.nih.gov/pubmed/36834591
http://dx.doi.org/10.3390/ijms24043181

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