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Immunomodulator comedication promotes the reversal of anti-drug antibody-mediated loss of response to anti-TNF therapy in inflammatory bowel disease

PURPOSE: Loss of therapeutic response (LOR) due to anti-drug antibodies (ADA) against tumor necrosis factor (TNF) inhibitors is common in patients with inflammatory bowel disease (IBD). We aimed to investigate whether immunomodulator comedication can reverse the immunogenic LOR to TNF inhibitors in...

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Detalles Bibliográficos
Autores principales: Stallhofer, Johannes, Guse, Jan, Kesselmeier, Miriam, Grunert, Philip Christian, Lange, Kathleen, Stalmann, Robert, Eckardt, Verena, Stallmach, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968255/
https://www.ncbi.nlm.nih.gov/pubmed/36840779
http://dx.doi.org/10.1007/s00384-023-04349-1