Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1

Tandem pore domain (K2P) potassium channels modulate resting membrane potentials and shape cellular excitability. For the mechanosensitive subfamily of K2Ps, the composition of phospholipids within the bilayer strongly influences channel activity. To examine the molecular details of K2P lipid modula...

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Detalles Bibliográficos
Autores principales: Schmidpeter, Philipp A. M., Petroff, John T., Khajoueinejad, Leila, Wague, Aboubacar, Frankfater, Cheryl, Cheng, Wayland W. L., Nimigean, Crina M., Riegelhaupt, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968290/
https://www.ncbi.nlm.nih.gov/pubmed/36841877
http://dx.doi.org/10.1038/s41467-023-36765-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968290/
https://www.ncbi.nlm.nih.gov/pubmed/36841877
http://dx.doi.org/10.1038/s41467-023-36765-w

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