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Immune activation of vaginal human Langerhans cells increases susceptibility to HIV-1 infection

Vaginal inflammation increases the risk for sexual HIV-1 transmission but underlying mechanisms remain unclear. In this study we assessed the impact of immune activation on HIV-1 susceptibility of primary human vaginal Langerhans cells (LCs). Vaginal LCs isolated from human vaginal tissue expressed...

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Detalles Bibliográficos
Autores principales: van Teijlingen, Nienke H., Eder, Julia, Sarrami-Forooshani, Ramin, Zijlstra-Willems, Esther M., Roovers, Jan-Paul W. R., van Leeuwen, Elisabeth, Ribeiro, Carla M. S., Geijtenbeek, Teunis B. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968315/
https://www.ncbi.nlm.nih.gov/pubmed/36841916
http://dx.doi.org/10.1038/s41598-023-30097-x