Long non-coding RNA-derived peptides are immunogenic and drive a potent anti-tumour response

Protein arginine methyltransferase (PRMT) 5 is over-expressed in a variety of cancers and the master transcription regulator E2F1 is an important methylation target. We have explored the role of PRMT5 and E2F1 in regulating the non-coding genome and report here a striking effect on long non-coding (...

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Detalles Bibliográficos
Autores principales: Barczak, Wojciech, Carr, Simon M., Liu, Geng, Munro, Shonagh, Nicastri, Annalisa, Lee, Lian Ni, Hutchings, Claire, Ternette, Nicola, Klenerman, Paul, Kanapin, Alexander, Samsonova, Anastasia, La Thangue, Nicholas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968330/
https://www.ncbi.nlm.nih.gov/pubmed/36841868
http://dx.doi.org/10.1038/s41467-023-36826-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968330/
https://www.ncbi.nlm.nih.gov/pubmed/36841868
http://dx.doi.org/10.1038/s41467-023-36826-0

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