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Cross-platform normalization enables machine learning model training on microarray and RNA-seq data simultaneously

Large compendia of gene expression data have proven valuable for the discovery of novel biological relationships. Historically, most available RNA assays were run on microarray, while RNA-seq is now the platform of choice for many new experiments. The data structure and distributions between the pla...

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Detalles Bibliográficos
Autores principales: Foltz, Steven M., Greene, Casey S., Taroni, Jaclyn N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968332/
https://www.ncbi.nlm.nih.gov/pubmed/36841852
http://dx.doi.org/10.1038/s42003-023-04588-6