Sestrin2: multifaceted functions, molecular basis, and its implications in liver diseases

Sestrin2 (SESN2), a highly conserved stress-responsive protein, can be triggered by various noxious stimuli, such as hypoxia, DNA damage, oxidative stress, endoplasmic reticulum (ER) stress, and inflammation. Multiple transcription factors regulate SESN2 expression, including hypoxia-inducible facto...

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Detalles Bibliográficos
Autores principales: Lu, Chunfeng, Jiang, Yiming, Xu, Wenxuan, Bao, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968343/
https://www.ncbi.nlm.nih.gov/pubmed/36841824
http://dx.doi.org/10.1038/s41419-023-05669-4