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A variational algorithm to detect the clonal copy number substructure of tumors from scRNA-seq data

Single-cell RNA sequencing is the reference technology to characterize the composition of the tumor microenvironment and to study tumor heterogeneity at high resolution. Here we report Single CEll Variational ANeuploidy analysis (SCEVAN), a fast variational algorithm for the deconvolution of the clo...

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Detalles Bibliográficos
Autores principales: De Falco, Antonio, Caruso, Francesca, Su, Xiao-Dong, Iavarone, Antonio, Ceccarelli, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968345/
https://www.ncbi.nlm.nih.gov/pubmed/36841879
http://dx.doi.org/10.1038/s41467-023-36790-9