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Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial

BACKGROUND: Sepsis prognosis correlates with antibiotic adequacy at the early phase. This adequacy is dependent on antibacterial spectrum, bacterial resistance profile and antibiotic dosage. Optimal efficacy of beta-lactams mandates concentrations above the minimal inhibitory concentration (MIC) of...

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Detalles Bibliográficos
Autores principales: Roux, Damien, Benichou, Nicolas, Hajage, David, Martin-Lefèvre, Laurent, de Prost, Nicolas, Lerolle, Nicolas, Titeca-Beauport, Dimitri, Boulet, Eric, Mayaux, Julien, Mégarbane, Bruno, Mahjoub, Khaoula, Carpentier, Dorothée, Nseir, Saad, Tubach, Florence, Ricard, Jean-Damien, Dreyfuss, Didier, Gaudry, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968363/
https://www.ncbi.nlm.nih.gov/pubmed/36840825
http://dx.doi.org/10.1186/s13613-023-01105-0