Artificial intelligence-based HDX (AI-HDX) prediction reveals fundamental characteristics to protein dynamics: Mechanisms on SARS-CoV-2 immune escape

Three-dimensional structure and dynamics are essential for protein function. Advancements in hydrogen-deuterium exchange (HDX) techniques enable probing protein dynamic information in physiologically relevant conditions. HDX-coupled mass spectrometry (HDX-MS) has been broadly applied in pharmaceutic...

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Detalles Bibliográficos
Autores principales: Yu, Jiali, Uzuner, Ugur, Long, Bin, Wang, Zachary, Yuan, Joshua S., Dai, Susie Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968663/
https://www.ncbi.nlm.nih.gov/pubmed/36910327
http://dx.doi.org/10.1016/j.isci.2023.106282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968663/
https://www.ncbi.nlm.nih.gov/pubmed/36910327
http://dx.doi.org/10.1016/j.isci.2023.106282

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