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Artificial intelligence-based HDX (AI-HDX) prediction reveals fundamental characteristics to protein dynamics: Mechanisms on SARS-CoV-2 immune escape
Three-dimensional structure and dynamics are essential for protein function. Advancements in hydrogen-deuterium exchange (HDX) techniques enable probing protein dynamic information in physiologically relevant conditions. HDX-coupled mass spectrometry (HDX-MS) has been broadly applied in pharmaceutic...
Autores principales: | Yu, Jiali, Uzuner, Ugur, Long, Bin, Wang, Zachary, Yuan, Joshua S., Dai, Susie Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968663/ https://www.ncbi.nlm.nih.gov/pubmed/36910327 http://dx.doi.org/10.1016/j.isci.2023.106282 |
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