Tenofovir antiviral drug solubility enhancement with β-cyclodextrin inclusion complex and in silico study of potential inhibitor against SARS-CoV-2 main protease (M(pro))

Tenofovir (TFR) is an antiviral drug commonly used to fight against viral diseases infection due to its good potency and high genetic barrier to drug resistance. In physiological conditions, TFR is less water soluble, more unstable, and less permeable, limiting its effective therapeutic applications...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohandoss, Sonaimuthu, Velu, Kuppu Sakthi, Stalin, Thambusamy, Ahmad, Naushad, Alomar, Suliman Yousef, Lee, Yong Rok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968670/
https://www.ncbi.nlm.nih.gov/pubmed/36874474
http://dx.doi.org/10.1016/j.molliq.2023.121544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968670/
https://www.ncbi.nlm.nih.gov/pubmed/36874474
http://dx.doi.org/10.1016/j.molliq.2023.121544

Ejemplares similares