Analysis of a rare progeria variant of Barrier-to-autointegration factor in Drosophila connects centromere function to tissue homeostasis

Barrier-to-autointegration factor (BAF/BANF) is a nuclear lamina protein essential for nuclear integrity, chromatin structure, and genome stability. Whereas complete loss of BAF causes lethality in multiple organisms, the A12T missense mutation of the BANF1 gene in humans causes a premature aging sy...

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Detalles Bibliográficos
Autores principales: Duan, Tingting, Thyagarajan, Srikantha, Amoiroglou, Anastasia, Rogers, Gregory C., Geyer, Pamela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968693/
https://www.ncbi.nlm.nih.gov/pubmed/36842139
http://dx.doi.org/10.1007/s00018-023-04721-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968693/
https://www.ncbi.nlm.nih.gov/pubmed/36842139
http://dx.doi.org/10.1007/s00018-023-04721-y

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