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Development and safety of PI3K inhibitors in cancer

The phosphatidylinositol 3-kinase (PI3K) signalling pathway regulates cell survival, proliferation, migration, metabolism and other vital cellular life processes. In addition, activation of the PI3K signalling pathway is important for cancer development. As a result, a variety of PI3K inhibitors hav...

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Detalles Bibliográficos
Autores principales: Yu, Miaomiao, Chen, Jiajia, Xu, Zhifei, Yang, Bo, He, Qiaojun, Luo, Peihua, Yan, Hao, Yang, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968701/
https://www.ncbi.nlm.nih.gov/pubmed/36773078
http://dx.doi.org/10.1007/s00204-023-03440-4