In silico analysis decodes transthyretin (TTR) binding and thyroid disrupting effects of per- and polyfluoroalkyl substances (PFAS)

Transthyretin (TTR) is a homo-tetramer protein involved in the transport of thyroid hormone (thyroxine; T4) in the plasma and cerebrospinal fluid. Many pollutants have been shown to bind to TTR, which could be alarming as disruption in the thyroid hormone system can lead to several physiological pro...

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Detalles Bibliográficos
Autores principales: Dharpure, Rupal, Pramanik, Subrata, Pradhan, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
In Silico
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968702/
https://www.ncbi.nlm.nih.gov/pubmed/36566436
http://dx.doi.org/10.1007/s00204-022-03434-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968702/
https://www.ncbi.nlm.nih.gov/pubmed/36566436
http://dx.doi.org/10.1007/s00204-022-03434-8

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