Cargando…

In silico analysis decodes transthyretin (TTR) binding and thyroid disrupting effects of per- and polyfluoroalkyl substances (PFAS)

Transthyretin (TTR) is a homo-tetramer protein involved in the transport of thyroid hormone (thyroxine; T4) in the plasma and cerebrospinal fluid. Many pollutants have been shown to bind to TTR, which could be alarming as disruption in the thyroid hormone system can lead to several physiological pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dharpure, Rupal, Pramanik, Subrata, Pradhan, Ajay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	In Silico
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968702/ https://www.ncbi.nlm.nih.gov/pubmed/36566436 http://dx.doi.org/10.1007/s00204-022-03434-8

Ejemplares similares

Application of toxicology in silico methods for prediction of acute toxicity (LD(50)) for Novichoks
por: Noga, Maciej, et al.
Publicado: (2023)

Uncertainty assessment of proarrhythmia predictions derived from multi-level in silico models
por: Kopańska, Karolina, et al.
Publicado: (2023)

Migration of styrene oligomers from food contact materials: in silico prediction of possible genotoxicity
por: Beneventi, Elisa, et al.
Publicado: (2022)

Predicting the in vivo developmental toxicity of benzo[a]pyrene (BaP) in rats by an in vitro–in silico approach
por: Wang, Danlei, et al.
Publicado: (2021)

A continuous in silico learning strategy to identify safety liabilities in compounds used in the leather and textile industry
por: March-Vila, Eric, et al.
Publicado: (2023)

Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS)
por: Ehrlich, Veronika, et al.
Publicado: (2023)

Managing and treating per- and polyfluoroalkyl substances (PFAS) in membrane concentrates
por: Tow, Emily W., et al.
Publicado: (2021)

Per- and polyfluoroalkyl substances (PFAS) exposure and thyroid cancer risk
por: van Gerwen, Maaike, et al.
Publicado: (2023)

Per- and polyfluoroalkyl substances (PFAS) and total fluorine in fire station dust
por: Young, Anna S., et al.
Publicado: (2021)

Trends in the Regulation of Per- and Polyfluoroalkyl Substances (PFAS): A Scoping Review
por: Brennan, Nicole Marie, et al.
Publicado: (2021)

Immunotoxicity of Per- and Polyfluoroalkyl Substances: Insights into Short-Chain PFAS Exposure
por: Woodlief, Tracey, et al.
Publicado: (2021)

Diet as an Exposure Source and Mediator of Per- and Polyfluoroalkyl Substance (PFAS) Toxicity
por: Roth, Katherine, et al.
Publicado: (2020)

Exposure to per- and polyfluoroalkyl substances (PFAS) and type 2 diabetes risk
por: Roth, Katherine, et al.
Publicado: (2022)

Per- and Polyfluoroalkyl Substances (PFAS) in PubChem: 7 Million and Growing
por: Schymanski, Emma L., et al.
Publicado: (2023)

A workflow to build PBTK models for novel species
por: Schneckener, Sebastian, et al.
Publicado: (2020)

Guidance for statistical design and analysis of toxicological dose–response experiments, based on a comprehensive literature review
por: Kappenberg, Franziska, et al.
Publicado: (2023)

Per- and Polyfluoroalkyl Substances (PFAS): Significance and Considerations within the Regulatory Framework of the USA
por: Langenbach, Blake, et al.
Publicado: (2021)

Survey of per- and polyfluoroalkyl substances (PFAS) in surface water collected in Pensacola, FL
por: da Silva, Bianca Ferreira, et al.
Publicado: (2022)

A Review on Removal and Destruction of Per- and Polyfluoroalkyl Substances (PFAS) by Novel Membranes
por: Das, Suman, et al.
Publicado: (2022)

An investigation into per- and polyfluoroalkyl substances (PFAS) in nineteen Australian wastewater treatment plants (WWTPs)
por: Coggan, Timothy L., et al.
Publicado: (2019)

Advancing per- and polyfluoroalkyl substances (PFAS) research: an overview of ATSDR and NCEH activities and recommendations
por: Rogers, Rachel D., et al.
Publicado: (2021)

Removal of per- and polyfluoroalkyl substances (PFAS) from water by ceric(iv) ammonium nitrate
por: Sun, Jun, et al.
Publicado: (2021)

Systematic Evidence Map for Over One Hundred and Fifty Per- and Polyfluoroalkyl Substances (PFAS)
por: Carlson, Laura M., et al.
Publicado: (2022)

Assembly and Curation of Lists of Per- and Polyfluoroalkyl Substances (PFAS) to Support Environmental Science Research
por: Williams, Antony J., et al.
Publicado: (2022)

The EU’s Per- and Polyfluoroalkyl Substances (PFAS) Ban: A Case of Policy over Science
por: Spyrakis, Francesca, et al.
Publicado: (2023)

Adsorption of Per- and Polyfluoroalkyl Substances (PFAS) and Microcystins by Virgin and Weathered Microplastics in Freshwater Matrices
por: Shi, Yucong, et al.
Publicado: (2023)

In silico studies on bacterial xylanase enzyme: Structural and functional insight
por: Dutta, Bhramar, et al.
Publicado: (2018)

Maternal Exposure to Per- and Polyfluoroalkyl Substances (PFAS) and Male Reproductive Function in Young Adulthood: Combined Exposure to Seven PFAS
por: Hærvig, Katia Keglberg, et al.
Publicado: (2022)

In silico analysis of squalene synthase in Fabaceae family using bioinformatics tools
por: Aminfar, Zahra, et al.
Publicado: (2018)

Perfluoroalkyl and polyfluoroalkyl substances (PFAS) and their effects on the ovary
por: Ding, Ning, et al.
Publicado: (2020)

In silico structural homology modeling of nif A protein of rhizobial strains in selective legume plants
por: Satyanarayana, Sadam D.V., et al.
Publicado: (2018)

In-Vitro and In-Silico Assessment of Per- and Polyfluoroalkyl Substances (PFAS) in Aqueous Film-Forming Foam (AFFF) Binding to Human Serum Albumin
por: Li, Wenting, et al.
Publicado: (2021)

Screening of anti-inflammatory phytocompounds from Crateva adansonii leaf extracts and its validation by in silico modeling
por: Thirumalaisamy, Rathinavel, et al.
Publicado: (2018)

Interaction of rs316019 variants of SLC22A2 with metformin and other drugs- an in silico analysis
por: Sajib, Abu Ashfaqur, et al.
Publicado: (2018)

Comment on “Maternal Exposure to Per- and Polyfluoroalkyl Substances (PFAS) and Male Reproductive Function in Young Adulthood: Combined Exposure to Seven PFAS”
por: Abraham, Klaus
Publicado: (2023)

An Outdoor Aging Study to Investigate the Release of Per- And Polyfluoroalkyl Substances (PFAS) from Functional Textiles
por: Schellenberger, Steffen, et al.
Publicado: (2022)

Select Per- and Polyfluoroalkyl Substances (PFAS) Induce Resistance to Carboplatin in Ovarian Cancer Cell Lines
por: Rickard, Brittany P., et al.
Publicado: (2022)

Outside the Safe Operating Space of a New Planetary Boundary for Per- and Polyfluoroalkyl Substances (PFAS)
por: Cousins, Ian T., et al.
Publicado: (2022)

Associations between Per- and Polyfluoroalkyl Substances (PFAS) and Cardiometabolic Biomarkers in Adults of Czechia: The Kardiovize Study
por: Maranhao Neto, Geraldo A., et al.
Publicado: (2022)

Uncovering per- and polyfluoroalkyl substances (PFAS) with nontargeted ion mobility spectrometry–mass spectrometry analyses
por: Kirkwood-Donelson, Kaylie I., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ict1hcuvcva8ta8it9delj5h2s