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Breakthrough: a first-in-class virtual simulator for dose optimization of ACE inhibitors in translational cardiovascular medicine

The renin–angiotensin–aldosterone-systems (RAAS) play a central role in the pathophysiology of congestive heart failure (CHF), justifying the use of angiotensin converting enzyme inhibitors (ACEi) in dogs and humans with cardiac diseases. Seminal studies in canine CHF had suggested that the pharmaco...

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Detalles Bibliográficos
Autores principales: Schneider, Benjamin K., Ward, Jessica, Sotillo, Samantha, Garelli-Paar, Catherine, Guillot, Emilie, Prikazsky, Marc, Mochel, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968717/
https://www.ncbi.nlm.nih.gov/pubmed/36843132
http://dx.doi.org/10.1038/s41598-023-30453-x