Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes

Acute myeloid leukaemia (AML) patients harbouring certain chromosome abnormalities have particularly adverse prognosis. For these patients, targeted therapies have not yet made a significant clinical impact. To understand the molecular landscape of poor prognosis AML we profiled 74 patients from two...

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Detalles Bibliográficos
Autores principales: Casado, Pedro, Rio-Machin, Ana, Miettinen, Juho J., Bewicke-Copley, Findlay, Rouault-Pierre, Kevin, Krizsan, Szilvia, Parsons, Alun, Rajeeve, Vinothini, Miraki-Moud, Farideh, Taussig, David C., Bödör, Csaba, Gribben, John, Heckman, Caroline, Fitzgibbon, Jude, Cutillas, Pedro R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968719/
https://www.ncbi.nlm.nih.gov/pubmed/36843114
http://dx.doi.org/10.1038/s41392-022-01288-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968719/
https://www.ncbi.nlm.nih.gov/pubmed/36843114
http://dx.doi.org/10.1038/s41392-022-01288-1

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